Intralesional Steroid Injection Singapore

Dr Liew Hui Min - The Skin Drs
Dr. Liew Hui Min

Intralesional steroid injection is a targeted treatment where corticosteroid medication is injected directly into specific areas of skin concern. This allows the medication to work precisely at the site without affecting the rest of the body. The treatment helps reduce inflammation, flatten raised scars or lesions, and improve the appearance and comfort of affected areas.

Image lesion steroid injection Image lesion steroid injection

Indications for Intralesional Steroid Injection

This treatment approach may be recommended for several specific skin conditions that benefit from direct steroid application.

Keloid scars: These are raised, thick scars that extend beyond the original injury site and can be itchy or uncomfortable.

Hypertrophic scars: Raised, thick scars that remain within the original wound but are prominent and noticeable.

Cystic acne or inflamed cysts: Large, painful, deep spots that don’t respond well to topical treatments and may take weeks to resolve naturally.

Alopecia areata: Patchy hair loss where the immune system mistakenly attacks hair follicles, causing smooth, round bald spots.

Nodular prurigo: Raised, scaly eczema itchy bumps that haven’t improved with topical treatments alone.

Benefits of Intralesional Steroid Injection

Intralesional steroid injection offers several advantages by delivering medication directly to the treatment area.

  • Improved texture and appearance

    Raised scars and thick lesions often become flatter and softer following treatment, with many patients noticing improvements within weeks.

  • Targeted treatment

    Medication works directly at the affected area.

  • Symptom relief

    Itching, tenderness, and discomfort associated with inflamed skin conditions typically improve as the inflammation reduces.

  • Enhanced response to other treatments

    Areas that haven’t responded well to creams or other topical treatments may show better improvement after intralesional injection.

  • Convenient treatment schedule

    Most conditions require only occasional treatments, typically spaced several weeks apart, rather than daily applications.

Intralesional Steroid Injection Techniques

Your dermatologist will select the most appropriate steroid preparation and injection technique based on your specific condition and treatment area. Your dermatologist will examine the treatment area, discuss your medical history, medication review, and explain the procedure to determine if this treatment is right for you. Side-effects of the treatment will also be discussed.

Triamcinolone acetonide

The most commonly used steroid for intralesional injection, available in different concentrations to suit various skin conditions. Higher concentrations may be used for thicker, more resistant or treatment naive lesions.

Diluted preparations

Lower concentration mixtures are often used for delicate areas such as the face or for patients who may be more sensitive to steroid treatments.

Multiple injection technique

For larger areas or extensive scarring, several small injections are placed across the treatment zone to ensure even distribution of medication.

Single point injection

Smaller lesions such as individual cystic spots or small scars typically require only one carefully placed injection.

Step-by-Step Procedure

The intralesional steroid injection process is typically completed within minutes.

Area examination and marking

Your dermatologist examines the treatment area and may mark specific injection points to ensure accurate medication placement.

Skin cleansing

The treatment area is thoroughly cleaned with antiseptic or alcohol solution to reduce any risk of infection during the procedure.

Topical anaesthesia (if needed)

For sensitive areas or nervous patients, a numbing cream may be applied and left for 20-30 minutes before injection, though many patients find this unnecessary.

Injection process

Using a fine needle, the steroid medication is injected directly into the lesion or scar tissue, with the dermatologist controlling the depth and amount precisely.

Post-injection assessment

The injection site is checked for proper medication distribution, and gentle pressure may be applied to prevent bleeding or bruising.

After Care and Recovery

Immediate Care

Keep the area clean and dry: Gently cleanse the injection site with mild soap and water, avoiding scrubbing or harsh products for 24-48 hours after treatment.

Apply cold compress if needed: A cool, damp cloth can be applied for 10-15 minutes if you experience any swelling or discomfort immediately following injection.

Avoid touching or rubbing: Resist the urge to touch, scratch, or massage the treated area, as this may interfere with the medication’s distribution and increase irritation risk.

Recovery Timeline

First few days: Some redness, mild swelling, or tenderness at the injection site is normal and typically resolves within 2-3 days of treatment.

One to two weeks: Initial improvements in symptoms such as itching or tenderness often become noticeable during this period, though visible changes may take longer.

Four to six weeks: Most patients begin to see visible improvements in scar flattening, lesion reduction, or skin texture during this timeframe following treatment.

Two months: Full treatment benefits are typically apparent by this point, helping your dermatologist assess whether additional sessions would be beneficial.

Follow-up Care

Scheduled review appointments: Your dermatologist will arrange follow-up consultations to monitor your progress. They will determine if additional treatments are needed which are typically spaced 4-12 weeks apart to allow proper healing and assessment between sessions.

Potential Risks and Complications

Intralesional steroid injection is generally safe when performed by a qualified dermatologist. Possible side effects include temporary skin lightening, minor thinning, or small dilated blood vessels at the injection site. Some patients may experience mild pain, swelling, or bruising, which usually resolves within a few days.

Frequently Asked Questions

How painful is intralesional steroid injection?

Most patients describe the sensation as a brief sharp pinch followed by mild pressure as the medication is injected. The discomfort is typically short-lived and well-tolerated, though topical numbing cream can be applied beforehand if you’re particularly sensitive.

Can I wear makeup or apply moisturiser after treatment?

You should avoid applying any products to the injection site for at least 24 hours to prevent irritation and allow proper healing. After this period, you can gradually return to your normal skincare routine using gentle, fragrance-free products.

Will the steroid injection affect my immune system?

Intralesional injection delivers medication directly to the treatment area with minimal absorption into your bloodstream, so it’s unlikely to affect your overall immune system. This targeted approach is much different from taking oral steroids, which have more widespread effects throughout the body. Frequent injections with a high volume / potent steroid less than 1 month apart is not recommended.

How many treatments will I need for my condition?

The number of treatments varies considerably depending on your specific condition, its severity, and how well you respond to the initial injection. Some patients see sufficient improvement after one or two sessions, while others may benefit from a series of treatments.

Dr Liew Hui Min - The Skin Drs

Dr Liew Hui Min

Dr. Liew Hui Min is an accredited consultant dermatologist from the Ministry of Health and the General Medical Council UK.

Her clinical interest includes:

  • Paediatric Dermatology,
  • Women’s Dermatology,
  • General Adult Dermatology.

Having trained in major London Hospitals, Dr Liew returned to Singapore in 2014 as a Consultant at KK Women’s and Children’s Hospital (KKH) where she specialised in paediatric, women, obstetric and vulva dermatology. Currently, Dr Liew practices at The Skin Drs. clinic located at Gleneagles Hospital.

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